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American Cruise Lines

American Cruise Lines specializes in small-ship cruising along the inland waterways and rivers of the United States. Traveling along scenic routes aboard a fleet of superb riverboats, guests will find all of the comforts of a luxury hotel while discovering intriguing attractions and sights along the Mississippi River.

American Cruise Lines’ modern paddle wheelers offer attentive crews and an intimate atmosphere with no more than 185 passengers on board. Guests enjoy highly personalized service, spacious staterooms with private balconies, gourmet cuisine, complimentary room service and a free open-bar cocktail hour every evening before dinner. Comfortable lounges, large observation decks and glass-enclosed dining rooms are ideal for guests to relax, socialize and observe passing scenery and wildlife.

Onboard entertainment includes riverlorians, local musicians and expert lecturers who will share insights about the local history, nature and culture of the destinations visited. The company’s ships are designed to easily navigate the Mississippi River and its tributaries, docking in the heart of each port and taking you where larger ships could never go. Featured shore excursions with professional guides offer guests in-depth views of museums, national parks, mansions and more.

River cruises are rated according to the quality of the vessel and its accommodations, the number of included amenities and activities both on and off the ship, and the level of service delivered. American Cruise Lines’ sailings are categorized as deluxe on the industry rating scale (budget, first class and deluxe).

Eagle on Mississippi River

Book Now and Save on American Cruise Lines!


  • Enjoy a free open-bar cocktail hour every evening before dinner. Click here for eligible departures.

  • Receive free shore excursions on select river cruises. Click here for eligible departures.

  • Save $400 per couple when you book nine months in advance. Click here for eligible departures.


    Click on the FASTDEAL# at left for more information about any vacation. All prices are per person, based on double occupancy, in US dollars.

     Days  Departs Starts in Ends in River Cruise Name Company Quality* Starting
    Price**
    Inc Air
    Starting
    Price**
    No Air
    Status
    Click # For
    More Info
    800-510-4002
    #T156076 8 Jun 3  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices  Sold Out
    #T156045 8 Jun 3  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T10133 5 Jun 4  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T29531 11 Jun 8  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T156083 8 Jun 10  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T156134 8 Jun 17  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T156448 8 Jun 17  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T156162 8 Jun 24  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T156449 8 Jul 1  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T10141 5 Jul 8  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T10176 5 Jul 12  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T72483 11 Jul 16  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T157029 8 Jul 22  Memphis,TN   St. Louis, MO  Mississippi River Cruise (Memphis to St. Louis) ACL   Deluxe   View Prices   
    #T157033 11 Jul 26  St. Louis, MO   New Orleans, LA  Mississippi River Gateway Cruise (St. Louis to New Orleans) ACL   Deluxe   View Prices   
    #T22214 8 Jul 29  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices  Sold Out
    #T157015 8 Aug 5  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T10063 8 Aug 5  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T156793 22 Aug 5  New Orleans, LA   St. Paul, MN  Complete Mississippi River Cruise ACL   Deluxe   View Prices   
    #T23646 8 Aug 12  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T22811 8 Aug 19  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T10119 8 Aug 26  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T22299 8 Aug 26  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T157016 8 Sep 2  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T10361 8 Sep 2  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T156779 15 Sep 9  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T23674 8 Sep 9  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T23112 8 Sep 16  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T23689 8 Sep 23  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T30042 11 Sep 23  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T23282 8 Sep 30  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T22385 8 Oct 3  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T22396 8 Oct 7  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T10573 8 Oct 10  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T28899 15 Oct 14  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T22636 8 Oct 17  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T28913 15 Oct 24  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T156520 8 Oct 28  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T20220 8 Oct 28  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices  Sold Out
    #T21029 8 Nov 4  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T10442 5 Nov 7  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T21380 8 Nov 11  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T21483 8 Nov 18  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T156684 8 Nov 18  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T21828 8 Nov 25  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T21931 8 Dec 2  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T156711 8 Dec 2  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T156319 8 Dec 9  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T156320 8 Dec 16  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T10039 8 Dec 22  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T156333 8 Dec 30  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T17501 8 Feb 20, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T33738 8 Feb 27, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T10623 8 Mar 3, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T18214 8 Mar 6, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T10687 8 Mar 10, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T34911 8 Mar 13, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T10730 8 Mar 17, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T56853 5 Mar 20, 2018  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T11142 8 Mar 24, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T18389 8 Mar 24, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T18629 8 Mar 31, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T45670 8 Mar 31, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T45886 8 Apr 7, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T18698 8 Apr 7, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T19440 8 Apr 14, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T20088 8 Apr 21, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T46273 8 Apr 21, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T46719 8 Apr 28, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T12073 8 Apr 28, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T12613 8 May 5, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T20880 8 May 5, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T21511 8 May 12, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T47030 8 May 12, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T47071 8 May 19, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T23560 8 May 19, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T47240 8 May 26, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T13158 8 May 26, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T13822 8 Jun 2, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T56929 5 Jun 3, 2018  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T56098 11 Jun 7, 2018  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T24183 8 Jun 9, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T47800 8 Jun 16, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T27622 8 Jun 23, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T48738 8 Jun 30, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T56941 5 Jul 7, 2018  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T57437 5 Jul 11, 2018  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T56266 11 Jul 15, 2018  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T55696 11 Jul 25, 2018  St. Louis, MO   New Orleans, LA  Mississippi River Gateway Cruise (St. Louis to New Orleans) ACL   Deluxe   View Prices   
    #T53793 8 Jul 28, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T54405 8 Aug 4, 2018  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T54940 22 Aug 4, 2018  New Orleans, LA   St. Paul, MN  Complete Mississippi River Cruise ACL   Deluxe   View Prices   
    #T55140 8 Aug 11, 2018  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T103240 8 Aug 18, 2018  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T54612 8 Aug 25, 2018  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T53798 8 Aug 25, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T54014 8 Sep 1, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T54672 8 Sep 1, 2018  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T55312 15 Sep 8, 2018  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T103416 8 Sep 8, 2018  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T103309 8 Sep 15, 2018  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T103451 8 Sep 22, 2018  St. Louis, MO   Nashville, TN  Cumberland River Cruise (St. Louis to Nashville) ACL   Deluxe   View Prices   
    #T56287 11 Sep 22, 2018  New Orleans, LA   St. Louis, MO  Mississippi River Gateway Cruise (New Orleans to St. Louis) ACL   Deluxe   View Prices   
    #T103349 8 Sep 29, 2018  Nashville, TN   St. Louis, MO  Cumberland River Cruise (Nashville to St. Louis) ACL   Deluxe   View Prices   
    #T54213 8 Oct 2, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T54238 8 Oct 6, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T54862 8 Oct 9, 2018  St. Paul, MN   St. Louis, MO  Upper Mississippi River Cruise (St. Paul to St. Louis) ACL   Deluxe   View Prices   
    #T55600 15 Oct 13, 2018  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T54351 8 Oct 16, 2018  St. Louis, MO   St. Paul, MN  Upper Mississippi River Cruise (St. Louis to St. Paul) ACL   Deluxe   View Prices   
    #T55615 15 Oct 23, 2018  St. Paul, MN   New Orleans, LA  Grand Heartland Cruise ACL   Deluxe   View Prices   
    #T27879 8 Oct 27, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T53040 8 Nov 3, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T57450 5 Nov 6, 2018  New Orleans, LA   New Orleans, LA  Highlights of the Mississippi River ACL   Deluxe   View Prices   
    #T29743 8 Nov 10, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T53194 8 Nov 17, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T30313 8 Nov 24, 2018  New Orleans, LA   Memphis,TN  Lower Mississippi River Cruise (New Orleans to Memphis) ACL   Deluxe   View Prices   
    #T53774 8 Dec 1, 2018  Memphis,TN   New Orleans, LA  Lower Mississippi River Cruise (Memphis to New Orleans) ACL   Deluxe   View Prices   
    #T14515 8 Dec 8, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T15337 8 Dec 15, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T15438 8 Dec 22, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    #T17261 8 Dec 29, 2018  New Orleans, LA   New Orleans, LA  Mississippi River Cruise (New Orleans Roundtrip) ACL   Deluxe   View Prices   
    CALL NOW!       THESE DEALS WON'T LAST FOREVER!       800-510-4002

    * Key to Quality Ratings

    Tours are classified according to the quality of amenities and accommodations.

    Budget = River cruises typically range from $100 to $200 per person, per day, plus airfare.
    First Class = River cruises typically range from $150 to $350 per person, per day, plus airfare.
    Deluxe = River cruises typically range from $250 to $650 per person, per day, plus airfare.

    ** The prices shown are U.S. dollars per person, based on double occupancy, and subject to availability. Prices quoted for land/cruise arrangements are subject to increase without notice. Once we have received your deposit, land/cruise prices are guaranteed. Air prices quoted via phone or email are subject to increase and are guaranteed only from the time that full payment is received. Also, air prices or air promotions mentioned on this site or on the phone do not include baggage fees imposed by airlines. Sorry, we are unable to offer air from countries other than the U.S. However, for those international customers who are able to arrange their own transportation to the trip origination city, we are able to offer the land/cruise portion of the package at the price quoted.

      800-510-4002 OR Click to inquire about a
    river cruise via e-mail

    Open Mon-Fri 7am to 10pm, Sat 8am to 8pm, Sun 9am to 8pm, CDT