MississippiRiverCruises.com
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American Cruise Lines specializes in small-ship cruising along the inland waterways and rivers of the United States. Each of the line’s vessels features spacious staterooms, an attentive crew and an intimate atmosphere. Guests will find all the comforts of a luxury hotel on board.

The company’s cruise fares are highly inclusive, as gourmet cuisine, wine and beer with meals, a daily open-bar cocktail hour, enriching onboard entertainment and a selection of complimentary excursions are covered in the upfront rate. Historians and riverlorians join every sailing, leading informal lectures and discussions about the regions explored.

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Limited-Time Offers: American Cruise Lines
Offers are subject to change or withdrawal at any time. Some discounts are not combinable with other promotions.
  • Save $800 to $2,000 per couple off select cruises. Click here.
  • Receive one free hotel night before your cruise when you book 9 months in advance. Click here.
  • Save $400 per couple when you book nine months in advance. Click here.
  • Enjoy a free open-bar cocktail hour every evening before dinner. Click here.
  • Receive free shore excursions on select river cruises. Click here.

American Cruise Lines (To view the full itinerary, dates and prices, click "See prices.")
Vacation name Days Begins in Ends in Company Quality From
North America
Lower Mississippi River Cruise (Memphis to New Orleans) 8 Memphis,TN New Orleans,
LA
ACL Deluxe See prices
Cumberland River Cruise (Nashville to St. Louis) 8 Nashville,
TN
St. Louis,
MO
ACL Deluxe See prices
Highlights of the Mississippi River 5 New Orleans,
LA
New Orleans,
LA
ACL Deluxe See prices
Lower Mississippi River Cruise (New Orleans to Memphis) 8 New Orleans,
LA
Memphis,TN ACL Deluxe See prices
Mississippi River Cruise (New Orleans Roundtrip) 8 New Orleans,
LA
New Orleans,
LA
ACL Deluxe See prices
Mississippi River Gateway Cruise (New Orleans to St. Louis) 11 New Orleans,
LA
St. Louis,
MO
ACL Deluxe See prices
Complete Mississippi River Cruise 22 New Orleans,
LA
St. Paul,
MN
ACL Deluxe See prices
Upper Mississippi River Cruise (St. Louis to St. Paul) 8 St. Louis,
MO
St. Paul,
MN
ACL Deluxe See prices
Cumberland River Cruise (St. Louis to Nashville) 8 St. Louis,
MO
Nashville,
TN
ACL Deluxe See prices
Mississippi River Gateway Cruise (St. Louis to New Orleans) 11 St. Louis,
MO
New Orleans,
LA
ACL Deluxe See prices
Upper Mississippi River Cruise (St. Paul to St. Louis) 8 St. Paul,
MN
St. Louis,
MO
ACL Deluxe See prices
Grand Heartland Cruise 15 St. Paul,
MN
New Orleans,
LA
ACL Deluxe See prices